- Jannik Sinner (1) beats Christopher O’Connell in straight sets (6-1, 6-4, 6-2) while Tommy Paul (14) beat Gabriel Diallo in four sets 6-7 (5), 6-3, 6-1, 7-6 (3).
- Jessica Pegula (6) through to last 16 after beating Jessica Bouzas Maneiro (6-3, 6-3) on Arthur Ashe
- Jack Draper (25) beats Botic van de Zandschulp, who sensationally knocked out Carlos Alcaraz (3), in straight sets.
- Top seed Iga Swiatek (1) in action later on against Anastasia Pavlyuchenkova